Table 1.
Patient and cycle characteristics compared between participants exposed and unexposed to sleep disordered breathing.
| Factor | Normal Breathing (AHI <5) | Sleep Disordered Breathing (AHI ≥5) | p-value |
|---|---|---|---|
| N | 13 | 17 | |
| Age, mean (SD) | 35.4 (5.1) | 31.4 (3.4) | 0.02 |
| BMI, mean (SD) | 31.6 (8.7) | 28.0 (5.3) | 0.17 |
| Race, n (%) | 0.41 | ||
| Asian | 0 (0%) | 2 (12%) | |
| Black/African American | 2 (15%) | 3 (18%) | |
| White | 11 (85%) | 12 (71%) | |
| Ethnicity, n (%) | 3 (23%) | 0 (0%) | 0.04 |
| Hispanic/Latino/Spanish origin | |||
| Primary Diagnosis | 0.21 | ||
| Diminished ovarian reserve | 1 (8%) | 1 (6%) | |
| Male factor | 2 (15%) | 4 (24%) | |
| Polycystic Ovary Syndrome | 1 (8%) | 7 (41%) | |
| Recurrent Pregnancy Loss | 1 (8%) | 0 (0%) | |
| Tubal factor | 1 (8%) | 0 (0%) | |
| Unexplained | 7 (54%) | 5 (29%) | |
| Polycystic Ovary Syndrome | 1 (8%) | 7 (41%) | 0.04 |
| Regular Cyclesa | 11 (85%) | 10 (59%) | 0.13 |
| Prior Parity, n (%) | 3 (23%) | 1 (6%) | 0.17 |
| Current Tobacco Use, n (%) | 0 | 1 (6%) | 0.37 |
| History of Tobacco Use, n (%) | 1 (8%) | 2 (12%) | 0.71 |
| Current Alcohol Use, n (%) | 5 (38%) | 5 (29%) | 0.60 |
| Number of Alcoholic Drinks per Week, n (%) | 0.23 | ||
| 0 | 8 (62%) | 12 (71%) | |
| 1 | 3 (23%) | 3 (18%) | |
| 2 | 2 (15%) | 0 (0%) | |
| 3+ | 0 (0%) | 2 (12%) | |
| Current Vape User, n (%) | 0 (0%) | 0 (0%) | |
| Anti-Mullerian Hormone, mean (SD) | 2.9 (1.9) | 4.5 (4.2) | 0.22 |
| Antral Follicle Count, mean (SD) | 18 (10) | 26 (11) | 0.04 |
| Cycle Numberb | 0.55 | ||
| 1 | 11 (85%) | 15 (88%) | |
| 2 | 1 (8%) | 1 (6%) | |
| 3 | 1 (8%) | 0 (0%) | |
| 4 | 0 (0%) | 1 (6%) | |
| Total Oocytesc, mean (SD) | 17 (10) | 14 (10) | 0.58 |
| Total Number of Metaphase II oocytesd, mean (SD) | 13 (8.6) | 12 (7.8) | 0.60 |
| Fertilization Ratee, mean (SD) | 0.90 (0.11) | 0.75 (0.27) | 0.08 |
| Total Embryos, mean (SD) | 8 (5.5) | 6 (5.6) | 0.24 |
| Proportion Undergoing an Embryo Transfer, n (%) | 11 (0.85) | 16 (0.94) | 0.39 |
| Fresh Transferf, n (%) | 9 (0.69) | 12 (0.71) | 0.94 |
| Day 3 Embryo Transfer, n (%) | 3 (0.23) | 3 (0.23) | 0.71 |
| Number of Embryos Transferred, mean (SD) | 1.12 (0.6) | 1.0 (0.63) | 0.46 |
| Preimplantation Genetic Testingg, n (%) | 1 (8%) | 1 (6%) | 0.84 |
Regular cycles defined as cycle length ranging between 21 and 35 days in length.
Cycle numbers refer to the IVF cycle performed, 1 indicating the patient’s first IVF cycle.
Total oocytes is the total number of oocytes obtained at the time of ultrasound-guided egg retrieval.
Metaphase II oocytes refers to the total number mature oocytes capable of being fertilized.
Fertilization rate refers to the total number of mature oocyte (Metaphase II oocytes) that successfully fertilize.
Fresh Transfer refers to an embryo transfer performed 5 days following oocyte retrieval of an embryo that was never cryopreserved.
Preimplantation genetic testing (PGT) is the pre-planned process of performing a multi-cellular biopsy of a day 5, 6, or 7 blastocyst-stage embryo to assess for chromosomal abnormalities.