TABLE 1.
Criterion 1 At least 2 of the following: |
An increase in the greatest occipital-frontal circumference adjusted for gestational age defined as crossing percentiles (if a plateau was reached this did not qualify) |
Bulging fontanelle or split sutures or sunsetting sign | |
Increasing hydrocephalus on consecutive imaging studies determined by increase in ratio of biventricular diameter to biparietal diameter according to the method of O’Hayon et al.34
| |
Head circumference > 95 percentile for gestational age; or
| |
Criterion 2
|
Presence of marked syringomyelia with ventriculomegaly; or
|
Criterion 3
|
Ventriculomegaly with symptoms of Chiari malformation (stridor, swallowing difficulties, apnea, bradycardia); or
|
Criterion 4 | Persistent CSF leakage from the myelomeningocele wound or bulging at the repair site |
From The New England Journal of Medicine, Adzick NS, Thom EA, Spong CY, et al. A randomized trial of prenatal versus postnatal repair of myelomeningocele, Volume 364, pp 993-1004. © 2011 Massachusetts Medical Society. Reprinted with permission from Massachusetts Medical Society.