Table 3.
Association of combined genotypes (C3435T and G2677T) with AR in AR and none AR cases
| Variable | AR (n = 36) |
None AR (n = 47) |
OR (95% CI) | P value |
|---|---|---|---|---|
| N (%) | N (%) | |||
| TT 3435 GG 2677 | 3 (8.3%) | 10 (21.3%) | Reference | |
| CC 3435 GT 2677 | 8 (22.2%) | 6 (12.8%) | 2.500 (0.918–6.806) | 0.073 |
| CC 3435 TT 2677 | 5 (13.9%) | 6 (12.8%) | 1.863 (0.647–5.363) | 0.249 |
| CT 3435 GG 2677 | 2 (5.6%) | 7 (14.9%) | 0.972 (0.298–3.172) | 0.962 |
| CT 3435 GT 2677 | 11 (30.6%) | 6 (12.8%) | 3.046 (1.155–8.033) | 0.024 |
| CT 3435 TT 2677 | 7 (19.4%) | 2 (4.3%) | 4.486 (1.375–14.639) | 0.013 |
| CC 3435 GG 2677 | 0 (0%) | 1 (2.1%) | - | 1 |
| TT 3435 GT 2677 | 0 (0%) | 6 (12.8%) | - | 1 |
| TT 3435 TT 2677 | 0 (0%) | 3 (6.4%) | - | 1 |
AR; acute rejection; N; number, OR; odds ratio, CI; confidence interval, C; cytosine, T; thymine, G; guanine. Logistic regression analysis was used. P < 0.05 is considered significant; OR < 1 is considered protective; OR > 1 is considered risky. Reference combined genotype was considered as TT 3435 GG 2677