Table 7.

Comparison of genetic variability in MDR 1 C3435T and G2677T between Egyptian health controls with controls from other studies

	MDR1 C3435T
First author/ Reference	Country	Control number	CC	CT	TT	C	T	HW p	FST vs. current
Korkor et al.; [current]	Egypt	80	16	40	24	0.450	0.550	0.928	-
[49].	Jordan	116	24	60	32	0.466	0.534	0.671	< 0.001
[49].	Sudan	131	69	55	7	0.737	0.263	0.348	0.045
[50].	Morocco	100	39	51	10	0.645	0.355	0.256	0.038
[51].	Bahrain	184	64	84	36	0.576	0.424	0.376	0.016
[52].	Iran	200	40	105	55	0.463	0.538	0.429	< 0.001
[53].	Turkey	150	30	80	40	0.467	0.533	0.382	< 0.001
[54].	Egypt	200	68	103	29	0.598	0.403	0.317	0.022
[8].	France	81	29	34	18	0.568	0.432	0.193	0.014
[14].	Germany	188	53	90	45	0.521	0.479	0.576	0.005
	MDR1 G2677T
First author/ Reference	Country	Control number	GG	GT	TT	G	T	HW p	FSTvs. current
Korkor et al.; [current]	Egypt	80	39	28	13	0.663	0.338	0.052	-
[33].	Iran	120	78	25	0	0.879	0.121	0.161	0.066
[55].	China	200	35	75	42	0.477	0.523	0.892	0.035
[56].	Brazil	106	42	42	19	0.612	0.388	0.151	0.003
[57].	England	285	94	135	42	0.596	0.404	0.571	0.005
[58].	Korea	632	120	214	103	0.519	0.481	0.690	0.021
[59].	Scotland	370	102	174	94	0.511	0.489	0.256	0.024

P value (P value number significant if ≤ 0.05). MRD1: multi drug resistant type 1, T: thymine, G: guanine, C; cytosine, Genotypes are expressed as number, alleles are expressed as frequencies; HW p, p value of Hardy Weinberg equation; Fst: Comparisons were done using pairwise fixation index (FST) comparison versus the current study