Table 3.

Interaction analysis of aMED and sleep disorder on mortality

aMED categories	Sleep Disorder	HR 95% CI	P value	P for interaction
All-cause mortality				0.184
Higher aMED	Without	1(Ref)
Median aMED	Without	1.27 (1.11 ~ 1.46)	< 0.001
Lower aMED	Without	1.38 (1.21 ~ 1.58)	< 0.001
Higher aMED	With	1(Ref)
Median aMED	With	1.28 (0.9 ~ 1.82)	0.173
Lower aMED	With	1.46 (1.02 ~ 2.1)	0.04
CVD mortality				0.033
Higher aMED	Without	1(Ref)
Median aMED	Without	1.19 (0.9 ~ 1.58)	0.216
Lower aMED	Without	1.08 (0.81 ~ 1.43)	0.607
Higher aMED	With	1(Ref)
Median aMED	With	1.26 (0.56 ~ 2.86)	0.576
Lower aMED	With	1.65 (0.75 ~ 3.61)	0.213
Cancer mortality				0.955
Higher aMED	Without	1(Ref)
Median aMED	Without	1.28 (0.98 ~ 1.67)	0.066
Lower aMED	Without	1.46 (1.13 ~ 1.88)	0.004
Higher aMED	With	1(Ref)
Median aMED	With	0.68 (0.3 ~ 1.54)	0.35
Lower aMED	With	1.48 (0.72 ~ 3.04)	0.285

Adjusted for age, sex, race (Mexican American, non-Hispanic white, non-Hispanic black, other races), education level (below high school, high school or equivalent, college or above), marital status (married, widowed, divorced, and never married), family PIR, BMI, smoking status, total energy intake, comorbidities including diabetes mellitus, hypertension, CHF, CHD, and stroke