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. 2023 Mar 2;22(10):1182–1195. doi: 10.1080/15384101.2022.2071565

Figure 7.

Figure 7.

Silencing of circ-OXCT1 repressed NSCLC tumor growth in vivo. After stably transfecting with sh-NC or sh-circ-OXCT1, H1650 cells were injected into nude mice (n = 5/group) to induce xenograft tumors. (a) The image of most representative tumors were presented. (b) Tumor volume was monitored every 7 days for 35 days. (c) Tumor weight was recorded on the 35th day. (d) Circ-OXCT1, miR-516b-5p and SLC1A5 expression were measured by qRT-PCR analysis. (e) SLC1A5 protein expression was detected by western blotting. (f-g) The SLC1A5 (f) and ki-67 (g) positive cells were stained by IHC assay. Data were showed as mean ± SD. ***P < 0.001 by unpaired t test (two-tailed).