Eight-week-old male WT mice were treated with vehicle control or 10 mg/kg/day of DCHP by oral gavage for 4 weeks. F1 descendants of control or DCHP-exposed sires were fed a ND or HFD for 9 weeks. Growth curve (A and D), final body weight (B and E), and fat mass (percentage of body weight) (C and F) of male and female F1 mice were measured (n = 9–12, two-way ANOVA followed by Bonferroni’s multiple comparison test). Statistically significant differences between ND and HFD fed F1 mice from control sires were indicated with * (*P < 0.05, **P < 0.01, and ***P < 0.001). Statistically significant differences between ND and HFD fed F1 mice from DCHP sires were indicated with † (†P < 0.05, ††P < 0.01, and †††P < 0.001).