Table 1. Demographic and clinical characteristics of studied groups (n = 90).
| Characteristics | Control gp (n = 18) |
Benign gp (n = 12) |
Malignant gp (n = 60) |
P-value |
|---|---|---|---|---|
| Age (years) (mean ± SD) | 48.94±10.42 48.94±10.42 |
36.09±8.10 36.09±8.10 |
52.07±10.24 52.07±10.24 |
0.251 0.001 0.0001 |
| Body mass index (BMI), kg/m2 (mean ± SD) | 32.62±7.23 32.62±7.23 |
27.94±3.49 27.94±3.49 |
34.48±6.44 34.48±6.44 |
0.317 0.347 0.171 |
|
Family History of Cancer n (%) Yes No |
14 (77.8%) 4 (22.2%) |
9 (75%) 3 (25%) |
41 (68.3%) 19 (31.7%%) |
0.704 |
|
Diabetes/Diabetes medications n (%) Yes No |
7 (38.9%) 11 (61.1%) |
4 (33.3%) 8 (66.7%) |
18 (30%) 42 (70%) |
0.775 |
|
Menopausal status n (%) Pre Post |
7 (38.9%) 11 (61.1) |
10 (83.3%) 2 (16.7%) |
26 (43.3%) 34 (56.7%) |
0.028 |
| mRNA expression of DDX43 (mean ± SD) | 3.33±6.64 3.33±6.64 |
3.1±3.57 3.1±3.57 |
1.47±1.75 1.47±1.75 |
0.507 0.119 0.018 |
| Serum DDX43 protein levels (ng/L) (mean ± SD) | 2148.4±2025.69 2148.4±2025.69 |
1902.3±1401.47 1902.3±1401.47 |
1905.8±1740.05 1905.8±1740.05 |
0.683 0.764 0.989 |