Table 3.
Stimulation of SCE by H2O2, camptothecin, and phleomycin in RAD9 and rad9 :: URA3 strains
Chemical agent | Stimulation in
RAD9 (YB163)a |
Stimulation in
rad9 :: URA3 (YB147) |
||
---|---|---|---|---|
His+/CFU × 106 (survival %) | Fold increaseb | His+/CFU × 106 (survival %) | Fold increaseb | |
Spontaneous | 16 ± 2 (100) | 1 | 15 ± 2 (100) | 1 |
0.04% H2O2 | 59 ± 12 (40) | 3.7 | 60 ± 20 (35) | 4 |
50 μg/ml camptothecin | 32 ± 7 (88) | 2 | 20 ± 3 (91) | 1.3 |
10 μM phleomycin | 33 ± 6 (41) | 2.1 | 17 ± 3 (45) | 1.1 |
For complete genotype, see Table 1.
His+ frequency with agent/spontaneous His+ frequency.