Fifty GPC sequences from ticks, animals, and clinical cases were selected with representative sequences from each clade of CCHFV and spanning the widespread geographical distribution of the virus. A phylogenic tree of the 50 sequences was generated using Geneious Tree Builder, and clades were assigned based on previous publications1,24. Percent identity and similarity was calculated using William Pearson’s lalign program run through the Swiss Institute of Bioinformatics ExPASy Bioinformatics Resource Portal (now available through the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) https://www.ebi.ac.uk/Tools/psa/lalign/). A color gradient was applied to the percent identity and similarity, with red highlighting areas with the lowest homology, and blue highlighting areas with the greatest homology to the Turkey2004 sequence.