Table 1: Predicted epitopes by type per GPC region.
Total number of predicted CTL and HTL epitopes from using the NetCTL 1.2 and NetMHCII 2.3 servers. Epitopes were aligned to the Turkey2004 GPC sequence to determine their corresponding GPC region.
| Number of Predicted Epitopes | |||||
|---|---|---|---|---|---|
| GPC Region | Type of Epitope | Total | |||
| CTL | HLA-DR | HLA-DQ | HLA-DP | ||
| MLD | 19 | 39 | 140 | 11 | 209 (19.1%) |
| MLD-GP38 * | 0 | 0 | 0 | 0 | 0 (0%) |
| GP38 | 41 | 94 | 17 | 25 | 177 (16.2%) |
| GP38-G N * | 1 | 0 | 0 | 0 | 1 (0.1%) |
| G N | 54 | 42 | 10 | 37 | 143 (13.1%) |
| G N -NS M * | 2 | 5 | 5 | 0 | 12 (1.1%) |
| NS M | 40 | 43 | 66 | 14 | 163 (14.9%) |
| NS M -G C * | 1 | 3 | 4 | 0 | 8 (0.7%) |
| G C | 98 | 130 | 100 | 52 | 380 (34.8%) |
| Total | 256 | 356 | 342 | 139 | 1093 (100%) |
Epitopes located across known cleavage sites (indicated with *) were excluded from further consideration.