Table 2: Predicted epitopes by type per selected multi-epitope region.
Eleven multi-epitope regions were selected from alignment of the predicted epitopes to the GPC to generate the multi-epitope antigen. The length in residues of each region, GPC protein the region originated from, and the number and type of predicted epitopes included in each selected region are shown. A total of 812 epitopes (75.7% of total predicted epitopes) were included within the selected regions.
| Number of Predicted Epitopes | |||||||
|---|---|---|---|---|---|---|---|
| Epitope Region | Length (AA) | GPC Protein | Type of Epitope | Total | |||
| CTL | HLA-DR | HLA-DQ | HLA-DP | ||||
| GPC-01 | 77 | MLD | 6 | 11 | 62 | 0 | 79 |
| GPC-02 | 40 | MLD | 4 | 15 | 63 | 0 | 82 |
| GPC-03 | 36 | GP38 | 9 | 19 | 0 | 7 | 35 |
| GPC-04 | 97 | GP38 | 17 | 52 | 14 | 18 | 101 |
| GPC-05 | 100 | GN | 32 | 9 | 7 | 35 | 83 |
| GPC-06 | 85 | NSM | 15 | 36 | 45 | 10 | 106 |
| GPC-07 | 63 | GC | 11 | 16 | 23 | 0 | 50 |
| GPC-08 | 56 | GC | 8 | 2 | 10 | 0 | 20 |
| GPC-09 | 101 | GC | 14 | 22 | 16 | 0 | 52 |
| GPC-10 | 58 | GC | 11 | 39 | 44 | 0 | 94 |
| GPC-11 | 92 | GC | 21 | 43 | 0 | 46 | 110 |
| Total | 148 | 264 | 284 | 116 | 812 | ||