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. Author manuscript; available in PMC: 2023 May 18.
Published in final edited form as: Life Metab. 2023 Apr 4;2(2):load014. doi: 10.1093/lifemeta/load014

Figure 2. Weight loss improves OXPHOS efficiency in skeletal muscle.

Figure 2

(a) Rates of Ca2+ uptake, SERCA ATP hydrolysis, and SERCA transport efficiency in skeletal muscle (n =8 for all groups). (b) Representative western blots of proteins involved in Ca2+ transport. (c) Skeletal muscle P/O ratio in fiber bundles isolated from gastrocnemius muscles (n =6 for LN, n =8 for OB, n =10 for WL). P-values indicate statistical significance between OB and WL groups. (d) Representative western blots of OXPHOS subunits and citrate synthase (CS) in isolated mitochondria. One-way ANOVA with multiple comparisons (a) or two-way ANOVA with Sidak multiple comparisons (c). P-values except in panel I indicate statistical significance between OB and WL groups. P-value in panel I shows statistical significance for correlation. Data are represented as mean ± SEM.