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. Author manuscript; available in PMC: 2023 May 18.
Published in final edited form as: Sci Signal. 2023 Mar 14;16(776):eabo2838. doi: 10.1126/scisignal.abo2838

Fig. 5. Simulation of noncanonical (NIK-mediated) pathway activation at different basal levels of IKK activity.

Fig. 5.

(A) The physiological NIK activity curve used as input for all subsequent heatmaps. (B) Surface plot of RelB:p52 (B:52) abundance in simulations with the physiological NIK activity curve and the indicated basal IKK abundances. (C) Heatmaps of the nuclear concentrations of the indicated NF-κB dimers in simulations with a physiological NIK activity curve with the indicated basal IKK abundances.