Table 1.

Participant Demographics (n = 18) and Disease Characteristics

Participant demographics	N = 18
Age, median (range)	41 years (18–61 years)
Female, n (%)	13 (72%)
Race, n (%)
Caucasian	17 (94%)
Other (not specified)	1 (6%)
Ethnicity, n (%)
Non-Hispanic	16 (89%)
Not known	2 (11%)
KPS at screening, median (range)	85 (60–100)
Genetic severity score
1. Tissue mosaic, n (%)	7 (39%)
2. Classic, n (%)	3 (17%)
3. Severe, n (%)	8 (44%)
Target meningioma	N = 18
Volume, median (range)	14.5 cc (3.3–68.2 cc)
Maximum linear dimension, median (range)	32.8 mm (20.3–62.9 mm)
Annualized growth rate at enrollment (%), mean/median	51%/33%
Nontarget meningiomas	N = 20
Number of participants	14
Volume, median (range)	2.8 cc (0.9–19.9 cc)
Annualized growth rate at enrollment (%), mean/median	38%/14%
Vestibular schwannomas	N = 21
Number of participants	16
Volume, median (range)	2.70 cc (0.3–4.2 cc)
Maximum linear measurement (median, range)	22.9 mm (10–37.2 mm)
Annualized growth rate at enrollment (%), mean/median	20%/13%