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. 2021 May 25;24(14):4718–4736. doi: 10.1017/S1368980021002184

Table 4.

Heat map of placebo-controlled randomised controlled trials and systematic reviews examining the effect of ergogenic aids according to the supplement and reported outcomes (n 87 studies)

Nutritional ergogenic supplement Study design Exercise/performance outcome Anthropometric outcome Body composition outcome
Branched chain amino acids (n 10)   RCT (n 6) 6(92,93,132,146,159,173) 2(93,132) 3(93,132,173)
  Systematic reviews (n 4) 3(17,24,33) 0 3(17,33,45)
Caffeine (n 25)   RCT (n 20) 20(54,58,68,70,81,84,96,122,124,131,134,136,152,153,155,157,166168,175) 0 0
Systematic reviews (n 5) 5(2527,36,38) 0 0
Carbohydrate replacement (n 4) RCT (n 4) 4(50,53,85,118) 1(118) 0
  Systematic reviews (n 0) 0 0 0
Collagen (n 2)   RCT (n 2) 2(116,178) 2(116,178) 2(116,178)
  Systematic reviews (n 0) 0 0 0
Creatine (n 28)   RCT (n 22) 21(55,57,6067,72,75,79,88,98,105,117,118,164,165,179) 10(60,61,72,86,88,98,105,118,164,179) 13(55,6063,67,72,75,86,88,117,164,165)
  Systematic reviews (n 6) 4(17,28,29,39) 0 4(17,20,23,39)
Exogenous ketones (n 3)   RCT (n 2) 2(114,137) 0 0
  Systematic reviews (n 1) 1(41) 0 0
Multivitamins (n 0)   RCT (n 0) 0 0 0
  Systematic reviews (n 0) 0 0 0
n-3 (n 17)   RCT (n 15) 14(71,73,77,82,99,110,112,115,125,127,135,156,163,170) 5(82,107,115,127,163) 5(73,77,127,163,192)
  Systematic reviews (n 2) 2(16,31) 1(31) 1(16)

Red colour = >5 studies identified; orange colour = 1–5 studies identified; light yellow colour = no studies identified.