Table 1.

QUADAS-2 assessment for quality and applicability of evidence in diagnostic accuracy studies [23]

Report*	Ref		Risk of bias				Applicability concerns
			Domain I Patient selection	Domain II Index test	Domain III Reference standard	Domain IV Flow & timing	Domain I Patient selection	Domain II Index test	Domain III Reference standard
Jendrny et al. (2020)	[46]
Grandjean et al. (2020)	[47]
Eskandari et al. (2021)	[48]	−DTE 1
		−DTE 2
Grandjean et al. (2021)	[49]
Essler et al. (2021)	[50]	−DTE 1
		−DTE 2
		−DTE 3
		−DTE 4
		−DTE 5
		−DTE 6
		−DTE 7
		−DTE 8
Hag-Ali et al. (2021)	[39]
Mendel et al. (2021)	[51]	−DTE 1
		−DTE 2
		−DTE 3
Angeletti et al. (2021)	[52]
Sarkis et al. (2022)	[53]
Vlachová et al. (2021) (pre)	[54]
Jendrny et al. (2021)	[55]	−DTE 1
		−DTE 2
		−DTE 3
		−DTE 4
		−DTE 5
Wurtz et al. (2021) (pre)†	[41]		()	()	()	()	()	()	()
Vesga et al. (2021)	[40]	−DTE 1
		−DTE 2
		−DTE 3
		−DTE 4
Maia et al. (2021)	[56]
ten Hagen et al. (2021)	[57]	−DTE 1
		−DTE 2
		−DTE 3
Grandjean et al. (2022)	[58]
Grandjean et al. (2022)	[59]
Devillier et al. (2022)	[60]	−DTE 1
		−DTE 2
Chaber et al. (2022)	[61]
Guest et al. (2022)	[62]	−DTE 1‡
		−DTE 2‡
		−DTE 3
Mancilla-Tapia et al. (2022)	[63]	−DTE 1
		−DTE 2
Maurer et al. (2022)	[44]	−DTE 1
		−DTE 2§	()
Kantele et al. (2022)	[43]	−DTE 1
		−DTE 2§	()
Grandjean et al. (2022)	[42]
Twele et al. (2022)	[64]	−DTE 1
		−DTE 2
		−DTE 3
ten Hagen et al. (2022)	[45]	−DTE 1§	()
		−DTE 2§	()
		−DTE 3§	()
		−DTE 4§	()
Demirbas et al. (2023)	[65]	−DTE 1
		−DTE 2
		−DTE 3

DTE = diagnostic test evaluation; Pre = preprint; Ref = reference.

low risk or concerns; high risk or concerns; unclear risk or concerns.

*Reports sorted by publication date. ^†Not enough information for appropriate assessment. ^‡DTE described in appendix. ^§DTE was conducted with cross-sectional patient selection and study design. However, additional samples had to be added to the study process due to low prevalence.