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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: J Hepatobiliary Pancreat Sci. 2022 Dec 5;30(5):558–569. doi: 10.1002/jhbp.1279

Table 3:

Comparison of perioperative outcomes of patients who underwent laparoscopic left lateral sectionectomy, stratified by tumor size

All
N = 1910
Tumor size ≤39mm
N = 1027
Tumor size 40– 69mm
N = 528
Tumor size 70– 99mm
N = 212
Tumor size
≥100mm
N = 143
Z-statistic & P-value for monotonic
trend
Open conversion, n (%) 63 (3.3%) 22 (2.1)% 18 (3.4%) 13 (6.1%) 10 (7.0%) Z=3.90;
P<0.001
Median operating time (IQR), min 160 (112–215) 155 (105–215) 157 (112–210) 180 (120–220) 180 (126–235) Z=3.84,
P<0.001
Median blood loss (IQR), ml 100 (50–200) 50 (30–153) 100 (50–200) 100 (50–250) 200 (50–300) Z=6.50;
P<0.001
Intraoperative blood transfusion, n (%) 60 (3.1%) 19 (1.9%) 16 (3.0%) 11 (5.2%) 14 (9.8%) Z=5.15;
P<0.001
Pringle maneuver applied, n (%) 365/1868 (19.5%) 157/1011 (15.5%) 99/514 (19.3%) 60 (28.8%) 48/135 (35.6%) Z=6.48;
P<0.001
Median postoperative stay (IQR), days 5 (3–6) 5 (4–6) 5 (3–6) 5 (3–6) 5 (3–6) Z=0.84;
P=0.399
Overall morbidity, n (%) 255/1909 (13.4%) 125/1026 (12.2%) 80/528 (15.2%) 32/212 (15.1%) 18/143 (12.6%) Z=0.97;
P=0.330
Major morbidity (Clavien-Dindo grade>2) 52/1909 (2.7%) 24/1026 (2.3%) 12/528 (2.3%) 8/212 (3.8%) 8/143 (5.6%) Z=2.17;
P=0.030
30-day readmission, n (%) 44/1901 (2.3%) 17/1021 (1.7%) 15/527 (2.8%) 7/211 (3.3%) 5/142 (3.5%) Z=1.99;
P=0.047
30-day mortality, n (%) 7 (0.4%) 2 (0.2%) 3 (0.6%) 1 (0.5%) 1 (0.7%) Z=1.19;
P=0.233
90-day mortality, n (%) 12 (0.6%) 4 (0.4%) 4 (0.8%) 3 (1.4%) 1 (0.7%) Z=1.34;
P=0.180
Close margins, n (%) 110/1902 (5.8%) 54/1020 (5.3%) 44/528 (8.3%) 6/212 (2.8%) 6/142 (4.2%) Z=−0.57;
P=0.571

Two-sided Cochran-Armitage or Jonckheere-Terpstra tests were used to evaluate the presence of a monotonic increasing or decreasing trend over the four tumor size categories, which was treated as an ordinal variable (i.e., Group 1: <40mm, Group 2: 40–69mm, Group 3: 70–99mm, Group 4: ≥100mm).

IQR interquartile range