TABLE 2.
The roles and functions of lncRNA MINCR in various cancers.
| Cancer type | Role | Related molecule and pathway | Functions | Methods | PMID |
|---|---|---|---|---|---|
| Non-small cell lung cancer | Oncogenic | Cyclin A; cyclin D; CDK2; CDK4; c-Myc | Proliferation; cell cycle; apoptosis | In vitro | 31481083 |
| Oncogenic | miR-126/SLC7A5 | Proliferation; apoptosis; migration | In vitro and in vivo | 30528230 | |
| Glioma | Oncogenic | miR-876-5p/GSPT1 | Proliferation; apoptosis; migration; invasion | In vitro and in vivo | 32333234 |
| Hepatocellular cancer | Oncogenic | — | Proliferation; migration; invasion | In vitro | 29550632 |
| Oncogenic | miR-107/β-catenin | Proliferation; apoptosis | In vitro | 32521894 | |
| Gallbladder cancer | Oncogenic | c-Myc; miR-26a-5p/EZH2 | Proliferation; cell cycle; apoptosis; migration; invasion; epithelial mesenchymal transformation | In vitro and in vivo | 27345740 |
| Colorectal cancer | Oncogenic | miR-708-5p/CTNNB1/Wnt/β-catenin | Proliferation; apoptosis; migration; invasion; epithelial mesenchymal transformation | In vitro and in vivo | 32535381 |
| Oral squamous cell carcinoma | Oncogenic | Wnt/β-catenin | Proliferation; apoptosis; migration; invasion; epithelial mesenchymal transformation | In vitro | 30777615 |
| Osteosarcoma | Oncogenic | Wnt/β-catenin | Proliferation; apoptosis; migration | In vitro and in vivo | 35767742 |
| Cervical cancer | Oncogenic | miR-28-5p/RAP1B | Migration | In vitro | 35632705 |