Table 4.
Disease association of the mutations
| Genotype | Case (n, %) | Control (n, %) | Crude OR (95 CI%) | p* |
|---|---|---|---|---|
| Promoter ( – 221) | ||||
| X/X | 71 | 82 | 1.0 | 0.205 |
| X/Y | 13 | 8 | ||
| Y/Y | 16 | 10 | 0.58 | |
| Promoter ( – 550) | ||||
| H/H | 60 | 91 | 4.0 | < 0.0001* |
| H/L | 25 | 4 | ||
| L/L | 15 | 5 | 0.30 | |
| Exons | ||||
| AA | 43 | 69 | 1.0 | |
| BB | 12 | 09 | 0.47 | 0.141 |
| AB | 04 | 01 | 0.16 | |
| CC | 14 | 10 | 0.45 | 0.073 |
| AC | 04 | 00 | 0 | |
| DD | 17 | 05 | 0.18 | 0.0008* |
| AD | 06 | 06 | 0.62 |
OR Odds ratio, CI confidence intervals, p*: by Chi-square test. *Disease association with allele. Gender is adjusted as an explanatory variable in the regression