TABLE 4.
Supplement use according to current endocrine therapy (ET) among participants with hormone receptor (HR)+ tumor status
| Supplement | No current ET, n (%) | Current ET, n (%) | Crude OR (95% CI) | Adjusted1 OR (95% CI) | P value |
|---|---|---|---|---|---|
| Vitamin/mineral (VM) | |||||
| Vitamin D | 217 (72.1) | 512 (81.3) | 1.7 (1.2–2.3) | 1.8 (1.3–2.7) | 0.001 |
| Calcium | 126 (42.0) | 379 (60.4) | 2.1 (1.6–2.8) | 2.4 (1.7–3.3) | < 0.001 |
| Multivitamin | 129 (42.7) | 265 (42.3) | 1.0 (0.7–1.3) | 1.1 (0.8–1.6) | 0.442 |
| Vitamin C | 99 (33.3) | 194 (31.2) | 0.9 (0.7–1.2) | 0.9 (0.7–1.3) | 0.722 |
| Vitamin B12 | 41 (13.5) | 80 (12.7) | 0.9 (0.6–1.4) | 1.0 (0.6–1.6) | 0.977 |
| Biotin | 32 (10.6) | 93 (14.7) | 1.5 (1.0–2.2) | 1.4 (0.9–2.3) | 0.173 |
| Magnesium | 28 (9.2) | 79 (12.5) | 1.4 (0.9–2.2) | 1.4 (0.8–2.2) | 0.223 |
| Zinc | 18 (5.9) | 39 (6.2) | 1.0 (0.6–1.9) | 1.0 (0.5–1.9) | 0.946 |
| Natural Product (NP) | |||||
| Probiotic | 85 (28.1) | 166 (26.3) | 0.9 (0.7–1.2) | 0.9 (0.6–1.3) | 0.611 |
| Turmeric | 70 (23.1) | 136 (21.6) | 0.9 (0.7–1.3) | 0.9 (0.6–1.3) | 0.523 |
| Fish oil/omega-3 fatty acids | 60 (19.8) | 161 (25.7) | 1.4 (1.0–2.0) | 1.6 (1.1–2.4) | 0.016 |
| Melatonin | 66 (21.8) | 136 (21.7) | 1.0 (0.7–1.4) | 1.1 (0.8–1.7) | 0.491 |
| Cannabis | 60 (19.8) | 93 (14.8) | 0.7 (0.5–1.0) | 0.6 (0.4–0.9) | 0.012 |
| Glucosamine2 | 28 (9.3) | 78 (12.4) | 1.4 (0.9–2.2) | 1.7 (1.0–2.9) | 0.065 |
| Flax | 46 (15.2) | 59 (9.4) | 0.6 (0.4–0.9) | 0.5 (0.3–0.8) | 0.006 |
| Ginger | 31 (10.2) | 57 (9.0) | 0.9 (0.6–1.4) | 0.7 (0.4–1.2) | 0.162 |
| Asian mushrooms | 24 (8.0) | 34 (5.4) | 0.7 (0.4–1.1) | 0.6 (0.3–1.1) | 0.116 |
1
Adjusted for age, geographic region, and race.
2
With or without chondroitin.