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. 2022 Dec 20;153(1):76–87. doi: 10.1016/j.tjnut.2022.10.010

TABLE 2.

Treatment feeds consumed for 28 d by male Mongolian gerbils in 2 studies. Gerbils were fed a provitamin A carotenoid (PAC), lycopene, and anthocyanin-free feed for 21 d before treatments and baseline measurements 1

Lycopene study Treatments Controls
Group (n) 1 (10) 2 (10) 3 (10) 4 (10) Positive (10) Negative (10)
Treatment feed2
 PAC3 + + + +
 Lycopene H MH ML L
 (nmol/g) 25.7 ± 5.88 19.6 ± 2.78 15.3 ± 4.11 9.42 ± 2.67
 Oil dose Vehicle Vehicle Vehicle Vehicle VA4 + Vehicle
Anthocyanin study
Group (n) 1 (10) 2 (10) 3 (10) 4 (10) Positive (10) Negative (10)
Treatment feed2
 PAC3 + + + +
 Lycopene4 + + + +
 Anthocyanins HA MHA MLA LA
 (μmol/g) 0.098 ± 0.18 0.083 ± 0.19 0.056 ± 0.15 0.038 ± 0.005
 Oil dose Vehicle Vehicle Vehicle Vehicle VA5 +/Lyc6 + Vehicle

H, high lycopene; HA, high anthocyanin; L, low lycopene; LA, low anthocyanin; Lyc, lycopene; MH, medium-to-high lycopene; MHA, medium-to-high anthocyanin; ML, medium-to-low lycopene; MLA, medium-to-low anthocyanin; PAC, provitamin A carotenoid; VA, vitamin A

1

Baseline group measurements were taken in n = 5 and 6 for the lycopene and anthocyanin studies, respectively.

2

Treatment feeds fortified with freeze-dried red (the lycopene study) and purple-red carrot (the anthocyanin study).

3

Equalized as BCE = β-carotene equivalents, 1 μg = 1 μg β-carotene or 2 μg α-carotene. BCE content of the 4 treatment feeds was 5.59 ± 0.96 μg/g in the lycopene study and 7.02 ± 0.39 μg/g in the anthocyanin study.

4

Lycopene content was 15.9 ± 0.95 nmol/g.

5

Provided as retinyl acetate in vehicle soybean oil, equalized to theoretical VA intake the prior day. The retinyl acetate concentrations were 0.874 and 2.03 nmol/μL for the lycopene and anthocyanin studies, respectively.

6

Provided as purified lycopene extracted from commercial supplements and dissolved in vehicle soybean oil with a final concentration of 2.19 nmol/μL.