Figure 2.
Differences in 18F-AV45 SUVR and DTI metrics between regions of WMH and NAWM. Violin plots representing the group differences in SUVR (left panel), FW (middle panel), and FW-adjusted FA (normalized to whole brain value; right panel) in the WMH (orange) vs. NAWM (green) across all subjects. Paired t-test showed significant differences between WMH and NAWM at *P < 0.0001 for all metrics. Specifically, SUVR and FW-adjusted FA were significantly lower and FW higher in WMH compared to NAWM. FA: fractional anisotropy; FW: free water; NAWM: normal appearing white matter; SUVR: standardized uptake value ratio; WMH: white matter hyperintensities.
