Association of age with cerebrovascular resistance (CVR) measured by
color-coded duplex ultrasonography (CDUS) (left upper and middle
panels), CVR index measured by transcranial Doppler (TCD) at the middle
cerebral artery (left lower panel), and Continued.vascular resistance in
the left (L) and right (R) internal carotid (ICA) and vertebral arteries
(VA) (right panels). CVR was calculated as mean arterial pressure
divided by total CBF (upper panel) and normalized CBF (middle panel).
Solid line, dotted line, dashed lines represent the regression equations
obtained for all subjects, men, and women, respectively. The rates of
increases in CVR and CVR index were similar between women and men
(p-values of the interaction of age and sex in one-way analysis of
covariance: CVR (left upper panel) p = 0.678; CVR (left middle panel)
p = 0.868; CVR index (left lower panel) p = 0.206; vascular resistance
LICA p = 0.986; RICA p = 0.789; LVA p = 0.261; RVA p = 0.893).