Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
NcRNA-regulated AS events mediate drug resistance in oncology. Some lncRNAs, miRNAs and circRNAs impact drug resistance of cancer cells by triggering AS of cell death-related genes and metabolism-related genes. AS of cell death-related genes decreases the ratio of pro-/anti-apoptotic splicing isoforms to promote apoptotic tolerance in tumor cells, while AS of metabolism-related genes causes the upregulation of PKM2 expression to promote glycolysis in cancer cells.
