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. 2023 Apr 29;13(8):2721–2733. doi: 10.7150/thno.83543

Figure 6.

Figure 6

Anti-inflammatory and angiogenesis activity of Cu-TCPP-Mn nanozyme in MI mice. (A) Representative immunofluorescence images and (B) quantitative analysis of heart tissues co-stained with CD31 (vessels, green), α-SMA (α-smooth muscle actin, red), and DAPI (cell nucleus, blue) in Sham and MI mice treated with PBS, Cu-TCPP, and Cu-TCPP-Mn. Scale bar, 200 μm (top), 20 μm (bottom). (C) Representative immunofluorescence images and (D) quantification analysis of heart tissues co-stained with CD45 (neutrophil cell, green), ACTN (Actinin, red), DAPI (cell nucleus, bule) in Sham and MI mice treated with PBS, Cu-TCPP, and Cu-TCPP-Mn. Scale bar, 100 μm. (E) Representative heart tissue sections stained with CD68 (brown) and DAPI (blue) (F) and quantification analysis in MI mice treated with PBS, Cu-TCPP, Cu-TCPP-Mn. Scale bar, 100 μm.