Table 2.

Half maximal inhibitory concentrations of hERG channels in planar patch clamp experiments by indicated Evodia extracts. Concentration response curves for hERG inhibition by EF5, EF4, EF7 and EP1 are illustrated in Fig. 3 A-D.

Extract	IC50 (µg/ml)
EF1	25,9 ± 4,8 (n = 3)
EF2	16,6 ± 2,9 (n = 4)
EP1	83,1 ± 16,1 (n = 3)
EF3	13,5 ± 1,9 (n = 4)
EP2	52,2 ± 5,9 (n = 3)
EF4	12,1 ± 3,2 (n = 3)
EF5	8,7 ± 1,1 (n = 3)
EP3	43,7 ± 11,1 (n = 3)
EP4	12,6 ± 5,9 (n = 3)
EP5	64,3 ± 16,7 (n = 3)
EF6	22,9 ± 14,7 (n = 3)
EF7	18,8 ± 3,6 (n = 4)