Table 2.
Clinical demographic overview of the study sample.
| Diagnosis | Age (years) | Sex | HDRSa score | YMRSb score | ||||
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|
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|
T0c | T1d | T2e | T0 | T1 | T2 |
| Manic BDf | 40 | Male | 5 | 4 | 4 | 24 | 8 | 2 |
| Manic BDg | 21 | Male | 3 | 5 | 4 | 23 | 15 | 1 |
| Depressed BDh | 33 | Male | 23 | 6 | 4 | 0 | 0 | 0 |
| Depressed BDg,h | 36 | Male | 17 | 12 | 3 | 2 | 4 | 2 |
| Mixed BD | 30 | Female | 8 | 4 | 4 | 30 | 20 | 5 |
| Mixed BDg | 40 | Male | 11 | 2 | 1 | 29 | 10 | 3 |
| Depressed MDDi | 57 | Male | 33 | 13 | 7 | 7 | 2 | 0 |
| Depressed MDDg | 45 | Male | 27 | 11 | 7 | 4 | 1 | 1 |
| Euthymic BD | 54 | Male | 3 | —j | — | 0 | — | — |
| Euthymic BDg | 61 | Male | 1 | — | — | 3 | — | — |
| Euthymic MDD | 60 | Female | 4 | — | — | 0 | — | — |
| Euthymic MDDg | 60 | Male | 3 | — | — | 0 | — | — |
| HCk | 32 | Female | 0 | — | — | 0 | — | — |
| HCg | 34 | Male | 0 | — | — | 0 | — | — |
| HC | 28 | Female | 0 | — | — | 1 | — | — |
| HC | 29 | Male | 0 | — | — | 2 | — | — |
| HC | 31 | Male | 2 | — | — | 1 | — | — |
| HC | 32 | Female | 1 | — | — | 3 | — | — |
| HC | 31 | Female | 0 | — | — | 1 | — | — |
aHDRS: Hamilton Depression Rating Scale.
bYMRS: Young Mania Rating Scale.
cT0: current acute Diagnostic and Statistical Manual of Mental Disorders–5 affective episodes or only register for euthymic patients and healthy controls.
dT1: symptoms’ response.
eT2: symptomatic remission.
fBD: bipolar disorder.
gThe recording segments extracted from the marked subjects were used to check the models’ ability to generalize to clinically similar subjects, unseen during training.
hAll registers performed at the hospitalization at home or outpatient units.
iMDD: major depressive disorder.
jEuthymic patients and healthy controls were recorded during a single session (T0).
kHC: healthy control.