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. Author manuscript; available in PMC: 2023 May 19.
Published in final edited form as: Biomater Adv. 2022 Aug 31;141:213093. doi: 10.1016/j.bioadv.2022.213093

Figure 7.

Figure 7.

Histomorphometric analysis of cementum formation and human PDLC localization in fenestration defects at 3 weeks. A-C) Overview scans of coronal sections of the first molar distal root in untreated (A), and AO (B) and MO hydrogel-treated (C) groups stained with hematoxylin and eosin with the locations of insets ia-ic, ii, and iii indicated by black outlines. A.ia-C.ia) insets demonstrating new bone (*) and acellular cementum formation (arrows). A.ib-C.ib) Adjacent sections stained for bone sialoprotein (BSP) (brown). B.ic-C.ic, C.ii-iii) Adjacent sections stained for human nuclear protein Ku80 (brown). Scale bars in overview scans are 1 mm, scale bars in insets are 100 μm. D) Percentage of root surface with new cementum. E) Percentage of Ku80+ within defects. N=6 rats. D) One-way ANOVA with Tukey post hoc. ***p<0.001. E) Unpaired t test.