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. 2023 May 19;49(2):220–235. doi: 10.1134/S1068162023020152

Table 2.

Lipid nanoparticle composition in the CVnCoV (CureVac) and ARCoV (Walvax) vaccines [59, 60]

Vaccine CVnCoV ARCoV
Manufacturer CureVac Walvax
mRNA dose, µg 12 5, 10, 15, 20 and 25
Components

Cationic Lipid (Acuitas Therapeutics)

Phospholipid

Cholesterol

PEG-lipid conjugate

Cationic lipid (no data)

Dystearoylphosphatidylcholine

Cholesterol

PEG-lipid conjugate

Ionizable cationic lipids : neutral lipids : cholesterol : PEGylated lipids (molar ratio, %) 50 : 10 : 38.5 : 1.5 50 : 10 : 38.5 : 1.5