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. 2023 May 8;14(10):1845–1858. doi: 10.1021/acschemneuro.3c00074

Table 4. Ratio of Ki Values with or without Phenytoin in the S1R Radioligand Binding Assay.

compound Ki (nM) control Ki (nM) + phenythoin ratio Ki (nM) control/+ phenythoin
4b 3.2 1.2 2.6
5b 12 14 0.9
8f 9.6 12 0.8
SKF-10,047 99 17 5.8
BD-1063 6.7 10 0.7