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. 2023 May 8;14(10):1717–1763. doi: 10.1021/acschemneuro.3c00127

Table 1. Gut Dysbiosis in Digestive System Diseases, Mental Health, and Metabolic Disorders.

diseases ↓ decreasing bacteria ↑ increasing bacteria
digestive system diseases
irritable bowel syndrome194199 Bifidobacterium Ruminococcus
Faecalibacterium prausnitzii Dorea
Bacteroides Enterobacteriaceae
Lactobacillaceae
Bacteroides
Firmicutes/Bacteroidetes ratio
IBD: Crohn’s disease200,201 Bacteroides  
Faecalibacterium prausnitzii
Bifidobacterium adolescentis
IBD: ulcerative colitis139,200 Bifidobacteria  
Roseburia hominis
Faecalibacterium prausnitzii
Lachnospiraceae
Ruminococcaceae
mental health disorders
anxiety disorder202,203 Bacteriodetes Bacteroidaceae
Ruminococcus gnavus Enterobacteriaceae
Fusobacterium Burkholderiaceae
post-traumatic stress disorder204 Actinobacteria  
Lentisphaerae
Verrucomicrobia
depression205207 Prevotella Eggerthella
Dialister Holdemania
Turicibacter
Paraprevotella
dementia172 Actinobacteria Escherichia
Bacteroides Blautia
Bifidobacterium
Streptococcus
Lactobacillus
Dorea
metabolic disorders
diabetes type 1208,209 Lactobacillus Clostridium
Bifidobacterium Bacteroides
Blautia coccoides Veillonella
Eubacterium rectale Actinobacteria
Prevotella Proteobacteria
Akkermansia Lactococcus
Firmicutes  
diabetes type 2199,209,210 Firmicutes Betaproteobacteria
Clostridia  
Lactobacillus Bacteroidetes/Firmicutes ratio
Akkermansia muciniphilia
Roseburia
obesity199,211 Bacteroidetes Enterobacteria
Methanobrevibacter smithii Ruminococcus gnavus
Ruminococcus flavefaciens Actinobacteria
Bifidobacterium Prevotellaceae