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[Preprint]. 2023 Nov 2:2023.05.09.539329. Originally published 2023 May 10. [Version 2] doi: 10.1101/2023.05.09.539329

Figure 2:

Figure 2:

Gene-level constraint estimates representing heterozygous selection coefficients on fitness, shet, from RGC-ME

A. Mean shet probability density for 16,704 canonical transcripts with 95% confidence intervals calculated with 10,000 bootstrapped samples from means of individual genes.

B. Odds ratio for genes with shet cutoff > 0.075 to be included in each gene category listed on y-axis.