Table 2.

Distinctions and overlaps of loci with mutations unique to the F. johnsoniae lines that were coevolved with B. thailandensis . These mutations were detected in at least one coevolved line and not present in any of the evolved F. johnsoniae monocultures

F. johnsoniae locus	Annotation	Rep 1	Rep 2	Rep 3	Rep 4	Rep 5
FJOH_RS00255	Acetyl-CoA carboxylase carboxyltransferase subunit alpha	–	–	C479A	–	–
FJOH_RS02320	Aminomethyl-transferring glycine dehydrogenase	–	–	–	–	Δ1 bp (504)
FJOH_RS04780	Hypothetical protein	G329C	–	–	–	–
FJOH_RS06580	TolC family protein	Δ33 bp (261–293)	Δ33 bp (261–293)	G247A	–	Δ33 bp (261–293)
FJOH_RS07830	NAD(P)/FAD-dependent oxidoreductase	–	C148A	–	–	–
FJOH_RS09515	LyTR family DNA-binding domain-containing protein	–	G46A	–	–	C44T
FJOH_RS09520	Histidine kinase	825insG	–	G496A	Δ1 bp (621)	–
FJOH_RS11170	Gfo/Idh/MocA family oxidoreductase	–	–	G273C	–	–
FJOH_RS12240	AIR synthase-related protein	–	–	C791T	–	–
FJOH_RS14175	Response regulator transcription factor	–	C269T	–	–	–
FJOH_RS20510	TetR/AcrR family transcriptional regulator	201insT	–	–	–	–
FJOH_RS21875	Glycoside hydrolase	T1489C	–	–	–	–
FJOH_RS24865	RagB/SusD family nutrient uptake outer membrane protein	–	–	–	793insG	–
FJOH_RS25290	Phosphoribosylanthranilate isomerase	–	–	–	T50C	–