Table 2.
The immunological characteristic of T cells in malignant effusion and blood.
| Name | Maliganat effusion | Blood | p value |
|---|---|---|---|
| Cytokines (pg/mL) | |||
| IL-2 | 1.867 ± 0.308 | 1.629 ± 0.184 | 0.5145 |
| IL-6 | 3311 ± 367.8 | 19.70 ± 5.045 | < 0.0001 |
| IL-10 | 64.28 ± 17.15 | 5.018 ± 1.446 | 0.0018 |
| IFN-γ | 18.47 ± 9.842 | 9.214 ± 1.635 | 0.3615 |
| TNF-α | 4.109 ± 0.793 | 5.609 ± 1.125 | 0.2852 |
| IL-4 | 4.151 ± 1.258 | 2.395 ± 0.268 | 0.1832 |
| Memory (%) | |||
| CD45RA in CD4 | 17.47 ± 3.130 | 28.36 ± 2.558 | 0.0195 |
| CD45RA in CD8 | 33.46 ± 5.087 | 49.69 ± 5.355 | 0.0484 |
| Residency (%) | |||
| CD69 in CD4 | 24.76 ± 7.395 | 3.939 ± 1.090 | 0.0165 |
| CD69 in CD8 | 53.43 ± 6.359 | 6.686 ± 1.762 | < 0.0001 |
| CD103 in CD4 | 2.693 ± 0.539 | 1.014 ± 0.173 | 0.0118 |
| CD103 in CD8 | 25.86 ± 6.714 | 3.136 ± 0.591 | 0.0046 |
| Cytokines (%) | |||
| IFN-γ in CD4 | 20.73 ± 3.580 | 17.10 ± 2.032 | 0.4805 |
| IFN-γ in CD8 | 30.78 ± 5.791 | 51.93 ± 7.088 | 0.0332 |
| TNF-α in CD4 | 39.35 ± 5.357 | 61.66 ± 4.644 | 0.0103 |
| TNF-α in CD4 | 35.99 ± 5.355 | 55.96 ± 7.548 | 0.0397 |
| Cytotoxicity (%) | |||
| Granzyme B in CD4 | 6.463 ± 1.390 | 8.640 ± 2.151 | 0.4079 |
| Granzyme B in CD8 | 33.14 ± 4.760 | 55.08 ± 7.174 | 0.0215 |
| Perforin in CD4 | 1.578 ± 0.621 | 6.269 ± 1.704 | 0.0199 |
| Perforin in CD8 | 4.480 ± 1.555 | 36.33 ± 6.915 | 0.0004 |
| Inhibitory receptor (%) | |||
| PD-1 in CD4 | 35.37 ± 8.084 | 15.68 ± 3.438 | 0.0446 |
| PD-1 in CD8 | 51.17 ± 11.27 | 17.93 ± 6.079 | 0.0234 |