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. 2023 Apr 17;14(7):1141–1150. doi: 10.7150/jca.83663

Figure 1.

Figure 1

Role of exosomes in ovarian cancer metastasis. Ovarian cancer-derived exosomes with their cargoes promote TAMs polarization, fibroblast recruitment and activation and transfer normal fibroblasts and PMCs into CAFs. Ovarian cancer-derived exosomes promote angiogenesis and EMT. Furthermore, CAF-derived exosomes also promote TAMs polarization, angiogenesis and EMT. TAMs-derived exosomes promoted the malignant phenotype of EOC. Created with BioRender.com.