Table 4.
SARS-CoV-2 Variants of Interest (VOI) and spike mutations identified globally, as of 23 February 2023 (https://www.ecdc.europa.eu/en/covid-19/country-overviews)
| WHO label | Lineage + additional mutations | Spike mutations of interest | Year and month first detected | Impact on | ||
|---|---|---|---|---|---|---|
| Transmissibility | Immunity | Severity | ||||
| Omicron | BA.2.75 | May 2022 | Unclear | Similar to baseline | No evidence | |
| Omicron | BQ.1 | K444T, N460K | Not available | Baseline | Baseline | Baseline |
| Omicron | XBB | N460K, F490S | Not available | Similar to baseline | Increased | No evidence |
| Omicron | XBB.1.5 | N460K, S486P, F490S | Not available | Increased | Increased | Similar to baseline |