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Tumor-driven exosomal circRNAs and immune infiltration in TME: A: Tumor cells regulate CD8+T cells and macrophages to participate in immune escape in TME by means of tumor-driven exosomal circRNAs; B: Tumor cells are involved in regulating PD1/PD-L1 drug resistance by regulating the secretion of cytokines by immune cells through exosome circRNAs; C: Tumor cells regulate immune cell-related tumor invasion and metastasis by means of tumor-driven exosomal circRNAs.
