The immunohistochemical characteristics follicular cell changes. (a) CK19 positivity (3+) in Follicles formed PTC-like nuclear cells (Immunoperoxidase, Original magnification x 400). (b) HBME-1 positivity (2+) in Follicles formed PTC-like nuclear cells (Red arrow, Immunoperoxidase, Original magnification x 400). (c) CK19 positivity (3+) in an atypical solid nodule (Red arrow, Immunoperoxidase, Original magnification x 400). (d) HBME-1 positivity (2+) in an atypical solid nodule (Red arrow, Immunoperoxidase, Original magnification x 400). (e) CK19 positivity (3+) in Hürthle cell metaplasia (Immunoperoxidase, Original magnification x 400. (f) HBME-1 positivity (2+) in Hürthle cell metaplasia (Immunoperoxidase, Original magnification x 400). (g) CK19 positivity (3+) in the Glomerular-like structure (Immunoperoxidase, Original magnification x 400. (h) HBME-1 positivity (2+) in the Glomerular-like structure (Immunoperoxidase, Original magnification x 400). (i) CK19 positivity (2+) in papillary strucrue, (Immunoperoxidase, Original magnification x 400). (j) HBME-1 positivity (2+) in papillary strucrue (Immunoperoxidase, Original magnification x 400)