Figure 1: Tregs suppress depigmentation in a mouse model of vitiligo.
(a) Total vitiligo scores from FoxP3-DTR mice treated with DTX or vehicle; (b) Representative images of ear and tail skin from FoxP3-DTR mice treated with PBS or DTX; (c) disease scores in the ear and tail (7 weeks post disease induction, N=12, two-tailed unpaired t test). (d) Sample flow plots and (e) quantification of Teffs in SDLN and skin of FoxP3-DTR mice treated with DTX (7 weeks post disease induction, N=8, two-tailed unpaired t test).