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. Author manuscript; available in PMC: 2023 May 19.
Published in final edited form as: ACS Chem Biol. 2020 Aug 10;15(8):2247–2258. doi: 10.1021/acschembio.0c00445

Figure 1.

Figure 1.

Enzymatic RNA labeling with RNA-TAG. Using bacterial tRNA Guanine Transglycosylase (TGT), an RNA of interest containing a 25 nucleotide TGT recognition hairpin is labeled with a derivative of the natural substrate, preQ1.