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. 2023 Apr 19;15(4):e37839. doi: 10.7759/cureus.37839

Table 2. Clinical manifestations among patients with LN and patients with SLE without LN post-index.

LN: lupus nephritis; SLE: systemic lupus erythematosus.

Clinical manifestations, n (%) LN (N=2310) SLE without LN (N=2310) p-value
Hematologic disorders 1143 (49.5) 666 (28.8) <0.001
Anemia 788 (34.1) 369 (16.0) <0.001
Thrombophilia 244 (10.6) 143 (6.2) <0.001
Thrombocytopenia 246 (10.7) 119 (5.2) <0.001
Neutropenia/leukopenia 188 (8.1) 109 (4.7) <0.001
Lymph node enlargement 117 (5.1) 79 (3.4) 0.004
Lymphadenopathy/splenomegaly 44 (1.9) 21 (0.9) 0.004
Arthralgia 1103 (47.8) 1240 (53.7) <0.001
Ophthalmologic disorders 523 (22.6) 558 (24.2) 0.219
Fever 363 (15.7) 203 (8.8) <0.001
Rash 222 (9.6) 245 (10.6) 0.256
Raynaud's phenomenon 175 (7.6) 190 (8.2) 0.422
Mouth ulcers 36 (1.6) 42 (1.8) 0.486