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. 2023 Apr 12;11:1158672. doi: 10.3389/fbioe.2023.1158672

TABLE 3.

Comparisons of advantages and disadvantages of various SARS-Cov-2 diagnosis methods.

Characteristics Detection methods
Gene sequencing Gene chip CLIA RT-LAMP CRISPR-cas RT-qpcr
Advantages High accuracy High degree of automation, high efficiency and low cost High sensitivity, high specificity, fast speed High sensitivity, simple operation, low equipment requirements High specificity High specificity and accurate results
Disadvantages Time-consuming and costly High requirements for equipment and operators High cost, high requirements for equipment and operators High false positive rate Low sensitivity High false negative rate, high requirements for equipment