TABLE 4.

Comparisons of various SARS-CoV-2 test methods based on CRISPR-Cas and RT-qPCR.

Detection method	Type of cas protein used	Target genes detected	Sensitivity (copy number/μl)	Specificity	Detection steps	Detection time (min)
RT-qPCR	Not Applicable	ORFlab, N	500	High	1	120
SHERLOCK	Cas13	ORFlab, S	10–100	High	3	60
STOPCovid.V2	Cas12b	N	100	High	1	15–45
AIOD-CRISPR	Cas12a	N	1.3	High	1	40
DETECTR	Cas12a	N, E	10	High	2	30
Opv-CRISPR	Cas12a	S	5	High	1	5