Table 1.
Case | Race/sex | Age at death | PMI (h) | ApoE | MMSE | Experiments |
---|---|---|---|---|---|---|
Control (n = 22) | ||||||
1 | AF | 57 | 17 | E3/3 | - | S T P |
2 | WM | 40 | 31 | E3/4 | - | S T P |
3 | AM | 59 | 6 | E2/3 | - | S T P |
4 | WF | 52 | 3 | E3/4 | - | S T P |
5 | WM | 57 | 10 | E3/3 | - | S T P |
6 | WF | 46 | 6.5 | E3/3 | - | S T P |
7 | AM | 53 | 6.5 | E4/4 | - | S T P |
8 | WF | 78 | 12 | E3/3 | 30 | S T P |
9 | WF | 92 | 16 | E3/3 | - | -- T P |
10 | WF | 45 | 28 | E3/3 | - | S T P |
11 | WM | 94 | 5.5 | E3/3 | 29 | S T P |
12 | AF | 43 | 15 | E3/3 | - | S T P |
13 | WF | 91 | 6 | E3/3 | - | S T P |
14 | WM | 56 | 13 | - | - | S T -- |
15 | AF | 61 | 6 | - | - | S T P |
16 | AM | 70 | 2.5 | E3/3 | 29 | S T P |
17 | WM | 51 | 23 | E2/3 | - | S -- -- |
18 | WF | 75 | 6 | E3/3 | - | S -- -- |
19 | WM | 69 | 6 | E3/3 | - | S T P |
20 | AM | 61 | 12 | E3/4 | - | S T P |
21 | WF | 74 | 7 | E3/3 | - | S -- P |
22 | WF | 74 | 3 | E3/3 | - | -- T P |
CAD (n = 9) | ||||||
1 | WM | 76 | 36 | E2/4 | 29 | S T P |
2 | WF | 64 | 17 | E4/4 | 30 | S -- -- |
3 | WM | 81 | 20 | E3/3 | 27 | S T P |
4 | WF | 82 | 38 | E3/4 | - | S -- -- |
5 | WM | 89 | 19 | E3/3 | 27 | S T P |
6 | WM | 80 | 5.5 | E3/4 | 28 | S T P |
7 | WM | 87 | 21 | E3/4 | 27 | S T P |
8 | WF | 87 | 5 | E2/3 | - | S T P |
9 | WF | 96 | 12 | E3/3 | - | -- T P |
AD (n = 33) | ||||||
1 | WM | 64 | 9 | E3/4 | - | S T P |
2 | WF | 87 | 6 | E3/4 | - | S T P |
3 | WF | 72 | 7 | E3/4 | - | S T P |
4 | WF | 64 | 4.5 | E3/4 | - | S T P |
5 | AF | 86 | 6 | E3/3 | 15 | S T P |
6 | WM | 71 | 15 | E3/4 | - | S T P |
7 | WM | 86 | 22 | E3/4 | - | S T P |
8 | WM | 67 | 6.5 | E2/3 | - | S T P |
9 | WF | 93 | 5 | E3/4 | 6 | -- T P |
10 | WM | 85 | 4 | E3/4 | 13 | S -- -- |
11 | WM | 91 | 22 | E3/3 | - | S T P |
12 | WM | 77 | 12 | E3/4 | - | S T P |
13 | WF | 94 | 4 | E3/4 | 19 | S T P |
14 | WM | 77 | 28 | E3/4 | 0 | -- T P |
15 | WM | 94 | 40 | E3/4 | 18 | -- T P |
16 | HM | 76 | 21 | E3/3 | 15 | S T P |
17 | WM | 83 | 5.5 | E3/4 | 10 | S T P |
18 | WM | 67 | 18 | E3/3 | - | S T P |
19 | AF | 66 | 16 | E3/4 | - | S T P |
20 | WM | 74 | 2.5 | E3/3 | 6 | S T P |
21 | WM | 62 | 6 | E2/3 | - | -- T P |
22 | WM | 68 | 15 | E3/3 | - | S T P |
23 | WF | 88 | 5 | E3/4 | 0 | -- T P |
24 | WM | 80 | 4 | E3/4 | 23 | S T P |
25 | AM | 86 | 7 | E4/4 | 12 | -- T P |
26 | WF | 80 | 6 | E3/4 | - | -- T P |
27 | AF | 80 | 5 | E3/4 | - | -- T P |
28 | WF | 91 | 5 | E3/4 | - | S -- -- |
29 | WM | 79 | 6 | E4/4 | - | S T P |
30 | F | 85 | 9.5 | E4/4 | - | S T P |
31 | WF | 81 | 12 | E3/4 | 0 | S T P |
32 | WF | 75 | 12 | E4/4 | - | S T P |
33 | WF | 93 | 16 | E3/4 | - | -- T P |
CAD = cognitively normal individuals with Alzheimer's disease pathology. A = African American. H = Hispanic. W = White. F = Female. M = Male. MMSE = Mini Mental State Examination. S = Spine Morphometry. T = Tau Quantification. P = Proteomics.