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. 2023 May 19;18(5):e0282878. doi: 10.1371/journal.pone.0282878

Fig 1. Progression of tissue through transformations to malignancy in model.

Fig 1

At each stage of transformation, tissue is acted on by processed of cell division (tissue growth), removal, and transformation to the next stage. Different classes of damage occur at different stages of progression. Individuals with malignant tissue are included in incidence statistics by a process of detection.