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. 2022 Nov 27;72(6):1933–1939. doi: 10.1007/s00262-022-03337-8

Table 1.

Clinical and pathological features of the study cohort

CRC patients
Number 45
Median age [range] 56 [18–79]
Gender [Male/Female] 30:15
TNM stage
I 4
II 20
III 14
IV 7
Tumor histological grade
G2 (Moderately differentiated) 41
G3 (Poorly differentiated) 4
MSI-H/dMMR 8
Loss of nuclear expression for MLH1 & PMS2 7
Loss of nuclear expression of MSH2 1
Molecular testing
KRAS mutations 4
BRAF mutations 1
NTRK gene fusion 1

CRC Colorectal cancer, MSI-H/dMMR high microsatellite instability /deficient mismatch repair