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. 2022 Sep 16;24(5):785–802. doi: 10.1007/s10198-022-01509-y
First-stage parameter estimates Estimate St. err. Prob. Chi sq.
Intervention characteristics
CABG fixed effect 0.3562 0.0345 < 0.0001
ICD/CRT fixed effect 0.1698 0.0268 < 0.0001
NSTEMI fixed effect 0.5518 0.0300 < 0.0001
STEMI fixed effect 0.0000
CABG readmission fixed effect − 3.3210 0.0249 < 0.0001
ICD/CRT readmission fixed effect − 3.0581 0.0147 < 0.0001
NSTEMI readmission fixed effect − 3.5410 0.0244 < 0.0001
STEMI readmission fixed effect − 2.9202 0.0206 < 0.0001
Patient characteristics
Age 0.0125 0.0019 < 0.0001
Age × age − 0.0001 0.0000 < 0.0001
Sex − 0.0247 0.0062 < 0.0001

Therapy

Anticoagulants

Antiplatelet

Anticoagulants × antiplatelet

− 0.1491

− 0.1014

− 0.0292

0.0094

0.0091

0.0117

< 0.0001

< 0.0001

0.0126

Elixhauser comorbidity groups (CABG, ICD/CRT)
Blood loss anemia − 0.2172 0.0214 < 0.0001
Hypertension, complicated 0.0317 0.0081 < 0.0001
Hypertension, uncomplicated 0.1519 0.0128 < 0.0001
Chronic pulmonary disease 0.0334 0.0078 < 0.0001
Depression − 0.0126 0.0079 0.1096
Drug abuse − 0.2003 0.0220 < 0.0001
Weight loss − 0.0177 0.0136 0.1922
Cardiac arrhythmia − 0.0194 0.0110 0.0779
Valvular disease − 0.0078 0.0079 0.3253
Congestive heart failure − 0.0157 0.0083 0.0580
Psychoses − 0.1566 0.0199 < 0.0001
Fluid and electrolyte disorders − 0.1256 0.0101 < 0.0001
Hypothyroidism − 0.0087 0.0086 0.3145
Metastatic cancer 0.1121 0.0180 < 0.0001
Solid tumor without metastasis 0.0349 0.0092 0.0001
Obesity − 0.0442 0.0081 < 0.0001
AIDS/HIV 0.0195 0.0779 0.8026
Alcohol abuse 0.0403 0.0148 0.0066
Rheumatoid arthritis/collagen − 0.0218 0.0089 0.0137
Diabetes, complicated − 0.0684 0.0093 < 0.0001
Diabetes, uncomplicated 0.0108 0.0105 0.3024
Peripheral vascular disorders − 0.0034 0.0079 0.6640
Coagulopathy − 0.0818 0.0093 < 0.0001
Liver disease − 0.0265 0.0083 0.0013
Pulmonary circulation disorders − 0.0847 0.0117 < 0.0001
Lymphoma − 0.0387 0.0233 0.0974
Paralysis − 0.1239 0.0134 < 0.0001
Deficiency anemia − 0.0635 0.0100 < 0.0001
Peptic ulcer disease, excluding bleeding − 0.0573 0.0145 < 0.0001
Other neurological disorders − 0.0070 0.0104 0.5012
Renal failure − 0.0888 0.0084 < 0.0001
Ontario AMI prediction rules, distance (NSTEMI/STEMI)
Shock 0.1195 0.0398 0.0027
Diabetes with complications − 0.0048 0.0112 0.6673
Congestive heart failure − 0.1452 0.0108 < 0.0001
Cancer 0.0129 0.0111 0.2441
Cerebrovascular disease − 0.0511 0.0106 < 0.0001
Pulmonary edema − 0.2782 0.0464 < 0.0001
Acute renal failure − 0.0787 0.0153 < 0.0001
Chronic renal failure − 0.0584 0.0126 < 0.0001
Cardiac dysrhythmias − 0.0176 0.0106 0.0960
Distance − 0.0005 0.0004 0.2656
Hospital characteristics
Teaching hospital 0.0336 0.0250 0.1797
Private for-profit hospital − 0.1737 0.0710 0.0144
Private not-for-profit hospital − 0.0206 0.0525 0.6949
Public hospital 0.0306 0.0503 0.5432
Beds − 0.0000 0.0001 0.89
Department admissions 0.0000 0.0000 < 0.0001
Department discharges − 0.0000 0.0000 0.7357
Specialist doc − 0.0001 0.0002 0.4384
Nurses 0.0000 0.0000 0.5551
Private for-profit hospital × beds 0.0001 0.0001 0.438
Private not-for-profit private × beds 0.0001 0.0001 0.4136
Public hospital × beds − 0.0000 0.0001 0.9105
Teaching hospital × beds − 0.0001 0.0000 0.0004
GRP inhabitant − 0.0000 0.0000 < 0.0001
DE East − 0.1180 0.1409 0.4022
DE West − 0.8525 0.3190 0.0075
452 hospital fixed effects included

Note: The AFT model assumes that a covariate accelerates or decelerates the survival time by a constant. We applied a transformation for a better interpretation of coefficients’ magnitude [62]