Table 4.
Top18 genes based on experimental design.
| gene_symbol | sum_score_h | ensgid | mouse_ensgid |
|---|---|---|---|
| FST | 94.7538168 | ENSG00000134363 | ENSMUSG00000021765 |
| ARRDC4 | 67.8910773 | ENSG00000140450 | ENSMUSG00000042659 |
| DEPP1 | 63.3306733 | ENSG00000165507 | ENSMUSG00000048489 |
| PNPLA5 | 55.1928157 | ENSG00000100341 | ENSMUSG00000018868 |
| FADS2 | 39.3079891 | ENSG00000134824 | ENSMUSG00000024665 |
| FASN | 34.9093403 | ENSG00000169710 | ENSMUSG00000025153 |
| ERBB3 | 32.1739147 | ENSG00000065361 | ENSMUSG00000018166 |
| YPEL3 | 30.926969 | ENSG00000090238 | ENSMUSG00000042675 |
| PCK1 | 29.4629409 | ENSG00000124253 | ENSMUSG00000027513 |
| MID1IP1 | 27.9817927 | ENSG00000165175 | ENSMUSG00000008035 |
| LPIN2 | 27.1569665 | ENSG00000101577 | ENSMUSG00000024052 |
| ATG2A | 24.6063739 | ENSG00000110046 | ENSMUSG00000024773 |
| ABCA9 | 24.3030494 | ENSG00000154258 | ENSMUSG00000041797 |
| OCLN | 23.7841083 | ENSG00000197822 | ENSMUSG00000021638 |
| GRB7 | 23.4696009 | ENSG00000141738 | ENSMUSG00000019312 |
| ANGPTL8 | 23.4366564 | ENSG00000130173 | ENSMUSG00000047822 |
| HSD17B11 | 22.3194899 | ENSG00000198189 | ENSMUSG00000029311 |
| NR1I3 | 20.2573204 | ENSG00000143257 | ENSMUSG00000005677 |
Top 18 genes based on consistent differential expression across different conditions (abs(“sum of sign”) in treated vs. CTR for human and mouse conditions >8) ranked by differential expression in human data set (sum_score_h = abs(sum(LogRatio * -log10padj across conditions).