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Nucleocapsid (N) antigenemia is superior to symptom duration as a diagnostic indicator of active infection. Receiver operating characteristic analysis (A–C), positive agreement (D), and negative agreement (E) with respect to nasopharyngeal swab virus culture, subgenomic ribonucleic acid (sgRNA), and N2 cycle threshold ([Ct] cutoff of ≤33). AUC, area under the receiver operating characteristic curve.
